Topical Clindamycin in Acne Treatment
Topical clindamycin in acne treatment acts in two ways: - It has antibacterial activity against P.acnes
- It decreases free fatty acids on the skin surface from 15-25%, thus reducing the inflammatory activity in the hair follicles.
Topical clindamycin in acne treatment is indicated in the treatment of mild, moderate and severe acne vulgaris, either alone or in combination with other anti-acne medications. Topical clindamycin in acne treatment is available as a topical gel or topical solution. Topical clindamycin gel may be applied to the affected areas in a thin layer twice daily. If used in combination, once daily application would suffice. Contraindications for the use of topical Clindamycin in acne treatment: - Individuals with a history of hypersensitivity to clindamycin should not use it
- A history of regional enteritis, ulcerative colitis or antibiotic associated colitis calls for caution and avoidance
- Any sign of diarrhea, bloody stools or colitis is a warning and the application should be immediately stopped.
- Topical clindamycin should not be used in pregnancy and lactation.
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