Topical Erythromycin in Acne Treatment

Topical Erythromycin in Acne Treatment

Topical erythromycin in acne treatment is a very effective drug in controlling the pustules in acne.

It penetrates into the hair follicle and acts against the bacteria as well as the lipases and other inflammatory mediators produced by P.acnes.

Topical erythromycin in acne treatment is available as 2% and 4% gels and 2% solution and 3% lotion. Twice daily application with 4% to start with, after 6-8 weeks, when improvement is noted, the concentration may be reduced to 2%.

• Adverse Effects of topical erythromycin in acne treatment are minimal and consists of Dryness, redness, burning sensation, pruritus, scaling etc.
• In case of dryness, emulsion may be used .
• Because of additive actions and competitive binding, topical erythromycin and clindamycin should not be used concurrently.

Other Topical Applications in Acne Treatment

Sodium Sulfacetamide 10% cream

Sodium sulfacetamide has good antibacterial properties, for better results it is combined with 5% Sulfur(e.g: Rosac Cream)

Sulfur 5% cream

Sulfur is an age old remedy. It has keratolytic activity on the skin and also inhibit growth of P.acnes and the formation of free fatty acids. In addition to acne, it is also used in acne rosacea and seborrheic dermatitis.

Contact irritant  and allergic dermatitis is a major concern with sulfur preparations. Any sign of irritation, redness or itchy eruptions calls for discontinuation.

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